Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781550 | 0.87 | FDPS (0.40) | ALDH1A3TBXAS1POLBWDR5TP53 | |
| SCHEMBL26328075 | 0.76 | TBXAS1 (0.36) | TBXAS1BRD4QPCTQPCTLESR1 | |
| SCHEMBL16589292 | 0.73 | TBXAS1 (0.39) | TBXAS1LMNABRD4IDO1TDO2 | |
| SCHEMBL23432572 | 0.70 | TBXAS1 (0.37) | TBXAS1ALDH1A1LMNABRD4CYP3A4 | |
| SCHEMBL31003223 | 0.70 | TBXAS1 (0.40) | TBXAS1ALDH1A1BRD4IDO1TDO2 | |
| SCHEMBL26826038 | 0.70 | NR3C1 (0.37) | TBXAS1BRD4IDO1ESR1 | |
| SCHEMBL2616777 | 0.70 | TBXAS1 (0.41) | TBXAS1POLBKMT2ATP53ALDH1A1 | |
| SCHEMBL20963444 | 0.69 | TBXAS1 (0.49) | TBXAS1LMNAIDO1ESR1 | |
| SCHEMBL17423771 | 0.69 | LMNA (0.50) | ALDH1A1LMNA | |
| SCHEMBL29303795 | 0.68 | EGLN1 (0.39) | TBXAS1TP53BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBL, STUB1 | ALDH1A3 4056/4885TBXAS1 2648/4885POLB 3920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.