Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10126868 | 0.70 | OPRD1 (0.37) | OPRD1FAAHALDH1A1CYP3A4MEN1 | |
| SCHEMBL12018912 | 0.70 | OPRD1 (0.37) | OPRD1FAAHALDH1A1CYP3A4MEN1 | |
| SCHEMBL7089368 | 0.68 | ALDH1A1 (0.39) | OPRD1OPRL1ALDH1A1MEN1KMT2A | |
| SCHEMBL31367138 | 0.65 | ELANE (0.48) | ALDH1A1CYP3A4KDM4EMEN1MAPT | |
| SCHEMBL1357343 | 0.65 | ALDH1A1 (0.43) | OPRD1ALDH1A1CYP3A4KDM4EMEN1 | |
| SCHEMBL21359992 | 0.63 | ELANE (0.31) | FAAHALDH1A1CYP3A4KDM4EMEN1 | |
| SCHEMBL3974883 | 0.61 | KMT2A (0.45) | OPRL1ALDH1A1CYP3A4MEN1MAPT | |
| SCHEMBL7672426 | 0.61 | NR3C2 (0.37) | OPRL1FAAHALDH1A1CYP3A4KDM4E | |
| SCHEMBL28219758 | 0.61 | CYP2D6 (0.47) | OPRD1OPRL1ALDH1A1CYP2D6 | |
| SCHEMBL12018913 | 0.60 | RAB9A (0.36) | ALDH1A1CYP3A4MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2296650-B1 | IMMUNOMODULATION BY IAP INHIBITORS | NOVARTIS AG (CH) | 2020-05-06 | — | — | EP | disclosed |