Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL357913 | 0.88 | — | — | |
| SCHEMBL5077002 | 0.82 | DNM1 (0.31) | — | |
| SCHEMBL5518932 | 0.80 | DNM1 (0.36) | — | |
| Potassium Ion SCHEMBL357059 | 0.79 | — | — | |
| SCHEMBL4965422 | 0.78 | — | — | |
| SCHEMBL21351043 | 0.72 | — | — | |
| SCHEMBL1149101 | 0.70 | — | — | |
| SCHEMBL1181188 | 0.70 | PTPN1 (0.31) | — | |
| SCHEMBL92464 | 0.69 | — | — | |
| SCHEMBL21351044 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344448-B1 | FLUOROALKYL ETHER SULFONATE SURFACTANTS | DU PONT (US) | 2013-03-20 | — | — | EP | disclosed |
| US-7977426-B2 | Fluoroalkyl ether sulfonate surfactants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-12 | — | — | US | disclosed |
| US-20100120980-A1 | FLUOROALKYL ETHER SULFONATE SURFACTANTS | E.I. DU PONT DE NEMOURS AND COMPANY | 2010-05-13 | — | — | US | disclosed |