Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24727169 | 0.87 | KIF11 (0.36) | KIF11AHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL26047684 | 0.84 | KIF11 (0.34) | KIF11AHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL27341382 | 0.84 | KIF11 (0.36) | KIF11AHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL18774270 | 0.79 | POLB (0.48) | KDM4EKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL18508330 | 0.79 | CDK4 (0.34) | KIF11KDM4EKMT2AALDH1A1HSD17B10 | |
| SCHEMBL18058376 | 0.78 | GPR3 (0.50) | KIF11AHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL18963101 | 0.78 | L3MBTL1 (0.43) | KDM4EKMT2AALDH1A1HSD17B10MEN1 | |
| SCHEMBL22751056 | 0.78 | TSPO (0.33) | TSPOPTGER4 | |
| SCHEMBL11689649 | 0.78 | AHR (0.50) | KIF11AHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL20962503 | 0.77 | TUBB4A (0.38) | KDM4EALDH1A1NPY5RRAB9ATSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |