Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.61 |
| ▸ | PPM1D | O15297 | 2/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23642786 | 0.96 | CYP4F2 (0.63) | CYP4F2CYP4A11PPM1DLOXL2CASR | |
| SCHEMBL7357651 | 0.86 | ACP1 (0.56) | CYP4F2CYP4A11PPM1DLOXL2PARP1 | |
| SCHEMBL4685289 | 0.85 | CYP4F2 (0.66) | CYP4F2CYP4A11PPM1DLOXL2PARP1 | |
| SCHEMBL15174341 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11PPM1DLOXL2 | |
| SCHEMBL2197741 | 0.84 | PPM1D (0.53) | PPM1DMRGPRX4FOLH1CYP2C9 | |
| SCHEMBL23022858 | 0.82 | PPM1D (0.60) | CYP4F2CYP4A11PPM1DLOXL2CASR | |
| SCHEMBL19922842 | 0.80 | CYP4A11 (0.60) | CYP4F2CYP4A11PPM1DLOXL2ALDH1A1 | |
| SCHEMBL70173 | 0.79 | CYP4F2 (0.83) | CYP4F2CYP4A11LOXL2PARP1SLC7A5 | |
| SCHEMBL1792728 | 0.78 | CYP4A11 (0.75) | CYP4F2CYP4A11LOXL2PARP1SLC7A5 | |
| SCHEMBL10606812 | 0.78 | CYP4A11 (0.75) | CYP4F2CYP4A11LOXL2PARP1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | CYP4F2 2970/4885CYP4A11 1728/4885PPM1D 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.