Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21976712 | 0.99 | LMNA (0.40) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL21976887 | 0.93 | MEN1 (0.39) | LMNAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL20682880 | 0.82 | METAP2 (0.45) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL17901243 | 0.82 | METAP2 (0.45) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL17901244 | 0.82 | METAP2 (0.45) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL17901133 | 0.81 | METAP2 (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL17901132 | 0.81 | METAP2 (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL20682901 | 0.81 | METAP2 (0.43) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL21985609 | 0.77 | RAB9A (0.40) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL21976920 | 0.77 | MTNR1A (0.45) | LMNACYP1A2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |