Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21976712 | 0.95 | LMNA (0.40) | MEN1ALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL21976725 | 0.93 | LMNA (0.41) | MEN1ALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL17901247 | 0.81 | METAP2 (0.36) | MEN1ALDH1A1KMT2ATSHRMTNR1A | |
| SCHEMBL21976920 | 0.81 | MTNR1A (0.45) | MEN1ALDH1A1KMT2ATSHRMTNR1A | |
| SCHEMBL21976754 | 0.77 | MTNR1A (0.45) | MEN1ALDH1A1KMT2ATSHRMTNR1A | |
| SCHEMBL17901132 | 0.76 | METAP2 (0.43) | MEN1ALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL20682901 | 0.76 | METAP2 (0.43) | MEN1ALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL17901133 | 0.76 | METAP2 (0.43) | MEN1ALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL974817 | 0.76 | MTNR1A (0.46) | MEN1ALDH1A1KMT2ATSHRMTNR1A | |
| SCHEMBL17901244 | 0.75 | METAP2 (0.45) | MEN1ALDH1A1KMT2ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240419-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-06 | — | — | EP | disclosed |