Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APC | P25054 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16468879 | 0.89 | CASP1 (0.58) | APCCASP1CASP3CASP9CTSB | |
| SCHEMBL2193938 | 0.85 | APC (0.60) | APCCASP1CASP3CASP9OPRD1 | |
| SCHEMBL30568689 | 0.84 | APC (0.57) | APCCASP1CASP3CASP9CTSB | |
| SCHEMBL2181857 | 0.84 | CASP1 (0.62) | APCCASP1CASP3CASP9CTSB | |
| SCHEMBL16770330 | 0.81 | CASP3 (0.62) | APCCASP1CASP3CASP9CTSB | |
| SCHEMBL30578421 | 0.79 | APC (0.57) | APCCASP1CASP3CASP9CTSB | |
| SCHEMBL6371162 | 0.78 | CASP1 (0.61) | CASP1CASP3CTSBCTSLCTSS | |
| SCHEMBL2873941 | 0.78 | MME (0.63) | CASP1CASP3CASP9CTSBCTSL | |
| SCHEMBL14778231 | 0.78 | MME (0.63) | CASP1CASP3CASP9CTSBCTSL | |
| SCHEMBL13589992 | 0.78 | ECE1 (0.63) | CASP1CASP3CASP9CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680263-B2 | Carbohydrate-based drug delivery polymers and conjugates thereof | NEKTAR THERAPEUTICS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171716-A1 | CARBOHYDRATE-BASED DRUG DELIVERY POLYMERS AND CONJUGATES THEREOF | STT3B, STT3A, DDOST | APC 1332/4885CASP1 4224/4885CASP3 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.