SCHEMBL2198478

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4347846	0.82	BRD4 (0.52)	BRD4IDO1MEN1KMT2AKDM4E
	SCHEMBL2198463	0.82	BRD4 (0.52)	BRD4CDC7
	SCHEMBL2196975	0.82	IKBKB (0.47)	BRD4KDM4EALDH1A1
	SCHEMBL2195873	0.81	BRD4 (0.47)	BRD4RAB9AMAPTKDM4ECDC7
	SCHEMBL4347544	0.80	BRD4 (0.47)	BRD4CDC7
	SCHEMBL2196845	0.80	CDC7 (0.51)	BRD4NPC1RAB9ACDC7
	SCHEMBL2196927	0.79	CDC7 (0.54)	BRD4MEN1KMT2ARAB9ASMN1; SMN2
	SCHEMBL2198773	0.77	KDM4E (0.44)	BRD4KDM4EALDH1A1
	SCHEMBL2198565	0.77	BRD4 (0.50)	BRD4KDM4ECDC7ALDH1A1
	SCHEMBL2199465	0.76	BRD4 (0.43)	BRD4CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.