Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929125 | 0.93 | TSHR (0.40) | TSHRKMT2AMEN1POLBHSD17B10 | |
| SCHEMBL22018085 | 0.85 | TSHR (0.36) | TSHRKMT2AMEN1POLBHSD17B10 | |
| SCHEMBL13724631 | 0.84 | ACHE (0.44) | TSHRKMT2APOLBHSD17B10 | |
| SCHEMBL1127852 | 0.83 | TSHR (0.39) | TSHRKMT2AMEN1LMNAHPGD | |
| SCHEMBL36036 | 0.83 | TSHR (0.45) | TSHRKMT2AMEN1LMNAPOLB | |
| SCHEMBL36226 | 0.82 | TSHR (0.40) | TSHRKMT2AMEN1LMNAPOLB | |
| SCHEMBL21089712 | 0.77 | LTA4H (0.40) | TSHRKMT2AMEN1LMNAPOLB | |
| SCHEMBL36030 | 0.77 | MEN1 (0.41) | TSHRKMT2AMEN1LMNAPOLB | |
| SCHEMBL36335 | 0.77 | TSHR (0.37) | TSHRKMT2AMEN1POLBHSD17B10 | |
| SCHEMBL36312 | 0.77 | TSHR (0.38) | TSHRKMT2AMEN1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3651223-A1 | ORGANIC ELECTRONICS MATERIAL AND ORGANIC ELECTRONICS ELEMENT | Hitachi Chemical Company, Ltd. (JP) | 2020-05-13 | — | — | EP | disclosed |