Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16242312 | 0.71 | KDM4E (0.33) | PTGS2 | |
| SCHEMBL2186389 | 0.71 | NOS3 (0.33) | — | |
| SCHEMBL28916752 | 0.69 | NT5E (0.33) | — | |
| SCHEMBL21986380 | 0.69 | — | — | |
| SCHEMBL25398144 | 0.69 | CA2 (0.38) | — | |
| SCHEMBL29988849 | 0.67 | LOXL2 (0.67) | LOXL2LOXKIF11TLR8 | |
| SCHEMBL3296352 | 0.67 | KIF11 (0.31) | KIF11 | |
| SCHEMBL9057494 | 0.67 | LOXL2 (0.67) | LOXL2LOXKIF11TLR8 | |
| SCHEMBL17079133 | 0.67 | HSP90AA1 (0.41) | LOXL2LOXTLR8PTGS2 | |
| SCHEMBL21597028 | 0.65 | HSP90AA1 (0.48) | LOXL2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019490-B1 | N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER | AGIOS PHARMACEUTICALS INC (US) | 2020-06-03 | — | — | EP | claimed |
| EP-3019490-B1 | N,6-BIS(ARYL OR HETEROARYL)-1,3,5-TRIAZINE-2,4-DIAMINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER | AGIOS PHARMACEUTICALS INC (US) | 2020-06-03 | — | — | EP | disclosed |