Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816045 | 0.85 | TSHR (0.32) | — | |
| SCHEMBL2186389 | 0.85 | NOS3 (0.33) | — | |
| SCHEMBL3290373 | 0.84 | GABRA2 (0.35) | KIF11 | |
| SCHEMBL3292713 | 0.72 | POLB (0.33) | — | |
| SCHEMBL16242312 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL18861629 | 0.72 | HSP90AA1 (0.43) | KIF11ACHE | |
| SCHEMBL25398144 | 0.71 | CA2 (0.38) | — | |
| SCHEMBL28916752 | 0.71 | NT5E (0.33) | — | |
| SCHEMBL3289169 | 0.71 | — | — | |
| SCHEMBL91323 | 0.69 | LOXL2 (0.48) | KIF11ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723384-B2 | Keto lactam compounds and use thereof | ABBOTT GMBH & CO. KG. (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1692129-B1 | KETO LACTAM COMPOUNDS AND USE THEREOF | ABBOTT GMBH & CO KG (DE) | 2008-08-20 | — | — | EP | disclosed |
| US-20070219182-A1 | Keto Lactam Compounds and Use Thereof | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219182-A1 | Keto Lactam Compounds and Use Thereof | OPRD1, DRD3, OPRK1 | KIF11 1639/4885ACHE 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.