SCHEMBL21991352

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21991934	0.93	GAA (0.48)	HPGDNPSR1PPARGPPARAMAPT
	SCHEMBL21991939	0.89	GAA (0.45)	NPSR1PPARGPPARAKMT2APTGS2
	SCHEMBL21991344	0.88	KMT2A (0.52)	HPGDNPSR1PPARGPPARAMAPK1
	SCHEMBL21992003	0.87	HPGD (0.47)	HPGDNPSR1PPARGPPARAMAPK1
	SCHEMBL21991592	0.86	L3MBTL1 (0.50)	MAPTMEN1LMNAKMT2ASMN1; SMN2
	SCHEMBL21991312	0.86	HPGD (0.55)	HPGDNPSR1PPARGPPARAMAPK1
	SCHEMBL21992719	0.86	HPGD (0.51)	HPGDNPSR1PPARGPPARAMAPK1
	SCHEMBL21991364	0.83	MAOB (0.52)	MAPTPTGS2ALDH1A1HTTRAB9A
	SCHEMBL21992699	0.81	MTNR1A (0.50)	HPGDPPARGPPARACYP1A2CYP2C9
	SCHEMBL21991987	0.80	KMT2A (0.45)	HPGDNPSR1PPARGPPARAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.