SCHEMBL21995253

SCHEMBL21995253

CN(CCCC(=O)OCc1ccccc1)C(=O)OCCl

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ALOX5 P09917 1/20 0.44
LMNA P02545 1/20 0.42
LTA4H P09960 2/20 0.42
MAPT P10636 2/20 0.41
HPGD P15428 1/20 0.41
EGFR P00533 2/20 0.40
F13A1 P00488 1/20 0.40
TGM2 P21980 1/20 0.40
TGM1 P22735 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
CCR6 P51684 1/20 0.40
PAX8 Q06710 1/20 0.40
CDC25B P30305 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25787612 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1LMNAMAPT
SCHEMBL16306384 0.85 ALDH1A1 (0.46) ALDH1A1MAPK1L3MBTL1ALOX5LTA4H
SCHEMBL5577016 0.84 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1ALOX5LMNA
SCHEMBL21995358 0.84 ALDH1A1 (0.42) ALDH1A1MAPK1L3MBTL1ALOX5LMNA
SCHEMBL25252134 0.83 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1LMNAMAPT
Hydrochloric Acid SCHEMBL4310487 0.83 LTA4H (0.53) ALDH1A1MAPK1L3MBTL1ALOX5LMNA
SCHEMBL25211503 0.83 L3MBTL1 (0.48) ALDH1A1MAPK1L3MBTL1ALOX5LMNA
SCHEMBL390750 0.82 ALDH1A1 (0.50) ALDH1A1MAPK1L3MBTL1LTA4HMAPT
SCHEMBL1225570 0.82 ALDH1A1 (0.49) ALDH1A1MAPK1L3MBTL1ALOX5MAPT
SCHEMBL393422 0.82 HTT (0.52) ALDH1A1MAPK1L3MBTL1ALOX5LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4566608-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2025-06-11 EP disclosed
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2025-06-05 US disclosed
EP-4440702-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
EP-4445900-B1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES INC (US) 2025-05-21 EP disclosed
US-12187753-B2 Therapeutics compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2025-01-07 US disclosed
EP-4445900-A2 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION Gilead Sciences, Inc. (US) 2024-10-16 EP disclosed
EP-4440702-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2024-10-09 EP disclosed
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2024-04-25 US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 US disclosed
US-11787825-B2 Therapeutic compounds for HIV virus infection GILEAD SCIENCES, INC. (US) 2023-10-17 US disclosed
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. 2023-06-29 US disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 WO disclosed
WO-2023102239-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION GILEAD SCIENCES, INC. (US) 2023-06-08 WO disclosed
US-20220106595-A1 ANTIBACTERIAL ANTISENSE AGENTS Pedanius Therapeutics Limited (GB) 2022-04-07 US disclosed
EP-3887520-A1 ANTIBACTERIAL ANTISENSE AGENTS Pedanius Therapeutics Limited (GB) 2021-10-06 EP disclosed
WO-2020109792-A1 ANTIBACTERIAL ANTISENSE AGENTS Pedanius Therapeutics Limited (GB) 2020-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179102-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS ALDH1A1 1512/4885MAPK1 4303/4885L3MBTL1 1204/4885
US-11787825-B2 Therapeutic compounds for HIV virus infection HAVCR2, MAVS, CD4 ALDH1A1 1718/4885MAPK1 4199/4885L3MBTL1 1303/4885
US-12187753-B2 Therapeutics compounds for HIV virus infection CD4, HAVCR2, MAVS ALDH1A1 1512/4885MAPK1 4303/4885L3MBTL1 1204/4885
US-20220106595-A1 ANTIBACTERIAL ANTISENSE AGENTS SLC47A1, SLC47A2, ZFR ALDH1A1 4038/4885MAPK1 3559/4885L3MBTL1 884/4885
US-20230203069-A1 THERAPEUTIC COMPOUNDS FOR HIV VIRUS INFECTION HAVCR2, MAVS, CD4 ALDH1A1 1718/4885MAPK1 4199/4885L3MBTL1 1303/4885
US-20240132527-A1 THERAPEUTICS COMPOUNDS FOR HIV VIRUS INFECTION CD4, HAVCR2, MAVS ALDH1A1 1512/4885MAPK1 4303/4885L3MBTL1 1204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.