Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21043087 | 0.81 | BRD4 (0.41) | BRD4NR3C1 | |
| SCHEMBL22001367 | 0.76 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1ALDH1A1KMT2AHTT | |
| SCHEMBL21043468 | 0.76 | CCR1 (0.31) | CCR1CCR5CCR8 | |
| SCHEMBL21043049 | 0.75 | ALDH1A1 (0.42) | BRD4SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL22001748 | 0.75 | ALDH1A1 (0.49) | SMN1; SMN2MEN1ALDH1A1KMT2AHTT | |
| SCHEMBL17371736 | 0.71 | ALDH1A1 (0.53) | SMN1; SMN2MEN1ALDH1A1KMT2AHTT | |
| SCHEMBL21043086 | 0.71 | CHRM1 (0.51) | — | |
| SCHEMBL16593262 | 0.71 | CHRM1 (0.51) | — | |
| SCHEMBL21042583 | 0.69 | SMN1; SMN2 (0.44) | BRD4SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL22001366 | 0.67 | ALDH1A1 (0.48) | SMN1; SMN2MEN1ALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-B1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2020-05-13 | — | — | EP | disclosed |