Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 6/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001366 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTSOS1KMT2A | |
| SCHEMBL22001367 | 0.85 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL22001371 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTSOS1KMT2A | |
| SCHEMBL21042787 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HTTSOS1KMT2A | |
| SCHEMBL21043049 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL19997556 | 0.79 | RPS6KB1 (0.42) | ALDH1A1SMN1; SMN2HTTKMT2AMAPT | |
| SCHEMBL21042783 | 0.78 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL21043468 | 0.76 | CCR1 (0.31) | — | |
| SCHEMBL21042583 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2HTTKMT2ALMNA | |
| SCHEMBL22001173 | 0.75 | BRD4 (0.44) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-B1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2020-05-13 | — | — | EP | disclosed |