Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001367 | 0.86 | SMN1; SMN2 (0.36) | CCR1CCR5CCR8 | |
| SCHEMBL22001173 | 0.76 | BRD4 (0.44) | CCR1CCR5CCR8 | |
| SCHEMBL22001748 | 0.76 | ALDH1A1 (0.49) | — | |
| SCHEMBL21043049 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL21043472 | 0.66 | NR3C1 (0.38) | — | |
| SCHEMBL21042583 | 0.64 | SMN1; SMN2 (0.44) | CCR1CCR5CCR8 | |
| SCHEMBL22001178 | 0.64 | POLB (0.39) | — | |
| SCHEMBL22001366 | 0.63 | ALDH1A1 (0.48) | — | |
| SCHEMBL21043082 | 0.61 | L3MBTL1 (0.42) | — | |
| SCHEMBL22001371 | 0.61 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |