Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852672 | 0.80 | TSHR (0.42) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL11956541 | 0.78 | ESR1 (0.37) | TDP1ALDH1A1ESR1ESR2MAPK1 | |
| SCHEMBL49520 | 0.76 | TSHR (0.48) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL9181403 | 0.76 | TSHR (0.48) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL717181 | 0.76 | TSHR (0.48) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL842024 | 0.76 | ESR1 (0.42) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL2275514 | 0.74 | ESR1 (0.41) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL7105315 | 0.74 | ALDH1A1 (0.43) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL49707 | 0.74 | ALDH1A1 (0.43) | TSHRTDP1ALDH1A1HSD17B10CTSD | |
| SCHEMBL16794738 | 0.74 | ALDH1A1 (0.43) | TSHRTDP1ALDH1A1HSD17B10CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883948-B2 | Methods for extensive dark curing based on visible-light initiated, controlled radical polymerization | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2014-11-11 | — | — | US | disclosed |
| US-20110166306-A1 | Methods For Extensive Dark Curing Based on Visible-Light Initiated, Controlled Radical Polymerization | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-07 | — | — | US | disclosed |
| WO-2010003026-A1 | METHODS FOR EXTENSIVE DARK CURING BASED ON VISIBLE-LIGHT INITIATED, CONTROLLED RADICAL POLYMERIZATION | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2010-01-07 | — | — | WO | disclosed |