SCHEMBL22005490

SCHEMBL22005490

CC(C)(C)OC(=O)CCNC(=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
HTT P42858 1/20 0.60
EPHX2 P34913 3/20 0.55
POLB P06746 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
GLA P06280 1/20 0.43
LMNA P02545 2/20 0.42
HSD11B1 P28845 2/20 0.42
MLYCD O95822 1/20 0.42
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14696502 0.76 EPHX2 (0.48) HTTEPHX2MEN1KMT2AGLA
SCHEMBL16064965 0.76 HTT (0.60) KDM4EHTTEPHX2POLBMEN1
SCHEMBL12137848 0.76 EPHX2 (0.44) KDM4EHTTEPHX2MEN1KMT2A
SCHEMBL8879807 0.76 KDM4E (1.00) KDM4EHTTEPHX2POLBMEN1
SCHEMBL27617726 0.75 EPHX2 (0.51) EPHX2MEN1KMT2AMLYCD
Hydrochloric Acid SCHEMBL1677927 0.74 EPHX2 (0.50) EPHX2MEN1KMT2AMLYCD
SCHEMBL17755397 0.74 HTT (0.57) KDM4EHTTEPHX2POLBMEN1
SCHEMBL6891227 0.73 ALDH1A1 (0.62) KDM4EHTTEPHX2POLBMEN1
SCHEMBL16064957 0.73 HTT (0.54) KDM4EHTTPOLBMEN1KMT2A
SCHEMBL28334704 0.72 KDM4E (0.68) KDM4EHTTEPHX2POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200159115-A1 NOVEL SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200159115-A1 NOVEL SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION, AND PATTERNING PROCESS ETV6, EEF2, EEF1G KDM4E 522/4885HTT 2117/4885EPHX2 2768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.