SCHEMBL2200581

SCHEMBL2200581

Nc1nc2ccccc2cc1S

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 9/20 0.53
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 4/20 0.53
GAA P10253 3/20 0.53
HPGD P15428 3/20 0.52
MAPT P10636 2/20 0.52
GLA P06280 2/20 0.52
ACHE P22303 1/20 0.52
HSD17B10 Q99714 1/20 0.52
IKBKB O14920 1/20 0.52
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
HTR3A P46098 1/20 0.48
ATM Q13315 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
PTBP1 P26599 1/20 0.47
RCE1 Q9Y256 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454362 0.77 TLR8 (0.57) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL359102 0.77 TLR8 (0.57) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL27880744 0.77 ALDH1A1 (0.56) TLR8ALDH1A1KDM4EGAAHPGD
Hydrochloric Acid SCHEMBL27365120 0.76 TLR8 (0.55) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL31123820 0.74 TLR8 (0.53) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL5745605 0.74 TDP1 (0.59) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL3300463 0.74 TLR8 (0.53) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL1133367 0.74 ALDH1A1 (0.59) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL1981418 0.74 TLR8 (0.53) TLR8ALDH1A1KDM4EGAAHPGD
SCHEMBL7915683 0.74 ALDH1A1 (0.52) TLR8ALDH1A1KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 TLR8 2674/4885ALDH1A1 1144/4885KDM4E 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.