SCHEMBL22006124

SCHEMBL22006124

CC(C)NC(=O)c1c(I)c(NC(=O)C(C)O)c(I)c(C(=O)NC(CO)CO)c1I

nearest known ligand 0.92

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.92
SMN1; SMN2 Q16637 1/20 0.33
PCNA P12004 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iopamidol SCHEMBL27781 0.96 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL471484 0.96 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL7101453 0.96 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL3424448 0.92 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL2140144 0.92 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL31409203 0.91 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL7709204 0.91 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL13283626 0.91 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL12142384 0.90 LMNA (0.83) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL22661225 0.88 LMNA (0.85) LMNASMN1; SMN2CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3485920-B1 COATING METHOD FOR A FOLDED BALLOON BRAUN MELSUNGEN AG (DE) 2020-05-20 EP disclosed