Iopamidol

Iopamidol

SCHEMBL471484

CC(O)C(=O)Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 1.00
SMN1; SMN2 Q16637 1/20 0.35
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iopamidol SCHEMBL7101453 1.00 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
Iopamidol SCHEMBL27781 1.00 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
SCHEMBL22006124 0.96 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL3424448 0.96 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL2140144 0.96 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
SCHEMBL31409203 0.95 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
SCHEMBL7709204 0.95 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL13283626 0.95 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL22661225 0.92 LMNA (0.85) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL15297031 0.92 LMNA (0.84) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090138-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-30 WO claimed
US-20260108635-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US claimed
EP-4172139-B1 PROCESS FOR THE PREPARATION OF IOPAMIDOL GE HEALTHCARE AS (NO) 2025-09-24 EP claimed
EP-4313934-B1 INDUSTRIAL SYNTHESIS OF SERINOL BRACCO IMAGING SPA (IT) 2025-05-07 EP claimed
US-20220105246-A1 COMPOSITIONS AND METHODS FOR TREATING THE VERTEBRAL COLUMN BIOMIMETIC THERAPEUTICS LLC (US) 2022-04-07 US claimed
EP-2975021-B1 PROCESS FOR THE PREPARATION OF IOPAMIDOL BRACCO IMAGING SPA (IT) 2017-07-26 EP claimed
EP-1353899-B1 A PROCESS FOR THE PREPARATION OF IOPAMIDOL BRACCO IMAGING SPA (IT) 2016-01-20 EP claimed
EP-2975021-A1 PROCESS FOR THE PREPARATION OF IOPAMIDOL Bracco Imaging SPA (IT) 2016-01-20 EP claimed
US-20160000972-A1 COMPOSITIONS AND METHODS FOR TREATING THE VERTEBRAL COLUMN STRYKER CORPORATION 2016-01-07 US claimed
US-20100183515-A1 COMPOSITIONS AND METHODS FOR TREATING THE VERTEBRAL COLUMN STRYKER CORPORATION 2010-07-22 US claimed
WO-2008151193-A1 COMPOSITIONS AND METHODS FOR TREATING THE VERTEBRAL COLUMN BIOMIMETIC THERAPEUTICS, INC. (US) 2008-12-11 WO claimed
US-7368101-B2 Process for the preparation of iopamidol and the new intermediates therein BRACCO IMAGING S.P.A. (IT) 2008-05-06 US claimed
US-20060106253-A1 Process for the preparation of iopamidol and the new intermediates therein BRACCO IMAGING S.P.A. (IT) 2006-05-18 US claimed
US-7034183-B2 Process for the preparation of iopamidol and the new intermediated therein BRACCO IMAGING S.P.A. (IT) 2006-04-25 US claimed
US-20040082812-A1 Process for the preparation of iopamidol and the new intermediated therein BRACCO IMAGING S.P.A. (IT) 2004-04-29 US claimed
EP-0901460-B1 A PROCESS FOR THE PREPARATION OF 5-AMINO-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLIC ACID DERIVATIVES BRACCO IMAGING SPA (IT) 2002-09-18 EP claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed
US-20260144748-A1 POLYOL-BASED MULTI-FUNCTIONAL COMPOUNDS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-28 US disclosed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US disclosed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106253-A1 Process for the preparation of iopamidol and the new intermediates therein C9, CBR3, INSR LMNA 1160/4885SMN1; SMN2 4416/4885CYP2C19 411/4885
US-20040082812-A1 Process for the preparation of iopamidol and the new intermediated therein INSR, ACVRL1, CBR3 LMNA 1132/4885SMN1; SMN2 3859/4885CYP2C19 493/4885
US-20260144748-A1 POLYOL-BASED MULTI-FUNCTIONAL COMPOUNDS FOR MEDICAL APPLICATIONS AND HYDROGELS FORMED FROM SAME CD44, PAM, PLOD3 LMNA 3220/4885SMN1; SMN2 3264/4885CYP2C19 1961/4885
US-20260108635-A1 ETHER-CONTAINING RADIOPAQUE POLYAMINO CROSSLINKERS AND MEDICAL HYDROGELS FORMED THEREFROM BRDT, ILK, KLK3 LMNA 3855/4885SMN1; SMN2 3806/4885CYP2C19 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.