Iopamidol

Iopamidol

SCHEMBL27781

C[C@H](O)C(=O)Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 1.00
SMN1; SMN2 Q16637 1/20 0.35
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iopamidol SCHEMBL471484 1.00 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
Iopamidol SCHEMBL7101453 1.00 LMNA (1.00) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
SCHEMBL22006124 0.96 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL3424448 0.96 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1A
Iopamidol SCHEMBL2140144 0.96 LMNA (0.92) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
SCHEMBL31409203 0.95 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1ACYP3A4
SCHEMBL7709204 0.95 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL13283626 0.95 LMNA (0.90) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL22661225 0.92 LMNA (0.85) LMNASMN1; SMN2CYP2C19HIF1A
SCHEMBL15297031 0.92 LMNA (0.84) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11584 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075768-A Degradable embolism microsphere with developing property and preparation method thereof 2026-05-26 CN claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
US-20260140444-A1 PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-05-21 US claimed
CN-122057065-A Ultrasonic-triggered enzymatic crosslinking hydrogel embolic agent and preparation method thereof 中山大学附属第五医院 2026-05-19 CN claimed
CN-122057084-A Valve clamp and preparation method thereof 科凯(南通)生命科学有限公司 2026-05-19 CN claimed
WO-2026101973-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-15 WO claimed
CN-122029126-A Method for obtaining iodide ions from a solution comprising an iodine-containing aromatic compound 伯拉考成像股份公司 2026-05-12 CN claimed
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-07 US claimed
EP-4259119-B1 EMBOLIZING EMULSION FOR TREATMENT OF INFLAMMATORY HYPERVASCULARIZATION ASSOCIATED WITH MUSCULOSKELETAL DISORDERS HOPITAUX PARIS ASSIST PUBLIQUE (FR) 2026-05-06 EP claimed
US-12616681-B2 Compositions and methods for treating renal injury CASE WESTERN RESERVE UNIVERSITY (US) 2026-05-05 US claimed
EP-0414288-A1 Contrast media NYCOMED IMAGING AS (NO) 1991-02-27 EP claimed
EP-0412280-A2 Fastening means BIOVISION GmbH Entwicklung, Herstellung und Vertrieb von Biomaterialien (DE) 1991-02-13 EP claimed
WO-1991001149-A1 CONTRAST MEDIA NYCOMED AS (NO) 1991-02-07 WO claimed
WO-1990011094-A1 CONTRAST MEDIA NYCOMED AS (NO) 1990-10-04 WO claimed
EP-0390242-A1 Contrast media NYCOMED IMAGING AS (NO) 1990-10-03 EP claimed
CN-1045528-A CONTRAST MEDIA NYCOMED AS (NO) 1990-09-26 CN claimed
WO-1989011272-A1 HIGH RATIO ACTIVE AGENT:LIPID COMPLEX THE LIPOSOME COMPANY, INC. (US) 1989-11-30 WO claimed
EP-0314764-A1 INJECTABLE OPACIFYING LIPOSOME COMPOSITION. BRACCO IND CHIMICA SPA (IT) 1989-05-10 EP claimed
WO-1988009165-A1 INJECTABLE OPACIFYING LIPOSOME COMPOSITION BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1988-12-01 WO claimed
EP-0128578-A1 Ethanolic suspensions of contrast agents Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1984-12-19 EP claimed