Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iopamidol SCHEMBL27781 | 0.95 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Iopamidol SCHEMBL471484 | 0.95 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Iopamidol SCHEMBL7101453 | 0.95 | LMNA (1.00) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Iopamidol SCHEMBL3424448 | 0.91 | LMNA (0.92) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL22006124 | 0.91 | LMNA (0.92) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Iopamidol SCHEMBL2140144 | 0.91 | LMNA (0.92) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL13283626 | 0.90 | LMNA (0.90) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL31409203 | 0.90 | LMNA (0.90) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Iopamidol SCHEMBL9490264 | 0.88 | LMNA (0.72) | LMNA | |
| SCHEMBL22661225 | 0.87 | LMNA (0.85) | LMNASMN1; SMN2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975021-B1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | BRACCO IMAGING SPA (IT) | 2017-07-26 | — | — | EP | claimed |
| US-5817861-A | Process for the preparation of an intermediate useful in the synthesis of iodinated contrast media | BRACCO INTERNATIONAL BV (NL) | 1998-10-06 | — | — | US | claimed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | claimed |
| US-6350908-B1 | MULTISTAGE REACTION WITH AMIDATION OF ACYL HALIDES WITH AMINOALKANEDIOLS AND HYDROLYSIS | BRACCO IMAGING S.P.A (IT) | 2002-02-26 | — | — | US | disclosed |
| US-5817861-A | Process for the preparation of an intermediate useful in the synthesis of iodinated contrast media | BRACCO INTERNATIONAL BV (NL) | 1998-10-06 | — | — | US | disclosed |
| US-5811581-A | CHROMATOGRAPHIC SEPARATION, NANOFILTRATION, DEIONIZATION ON ION EXCHANGE RESIN | DIBRA S.P.A. (IT) | 1998-09-22 | — | — | US | disclosed |
| US-5763663-A | REACTING 5-HYDROXY-2,4,6-TRIIODO-1,3-BENZENEDICARBOXYLIC ACID DIAMIDE WITH AMIDE HAVING REACTIVE SUBSTITUENT | DIBRA S.P.A. (IT) | 1998-06-09 | — | — | US | disclosed |
| US-5728877-A | ETHERIFICATION OF IODINATED BENZENEDICARBOXYLIC ACID AMIDES, INTERMEDIATES FOR X-RAY CONTRAST MEDIA | DIBRA S.P.A. (IT) | 1998-03-17 | — | — | US | disclosed |
| US-5689002-A | Process for the crystallization from water of (S)-N,N'-bis 2-hydroxy-1-(hydroxymethyl)ethyl!-5- 2-hydroxy-1-oxopropyl)amino!-2,4,6-triiodo-1,3-benzendicarboxamide | BRACCO INTERNATIONAL B.V. (NL) | 1997-11-18 | — | — | US | disclosed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |