Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | SLC19A1 | P41440 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 3/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | FPGS | Q05932 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24691541 | 0.81 | ALOX15 (0.44) | DHFRSLC19A1CRBNLMNAALOX15 | |
| SCHEMBL24290347 | 0.74 | GAA (0.42) | CRBNKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6651478 | 0.72 | DHFR (0.54) | DHFRSLC19A1TYMSLMNAALOX15 | |
| SCHEMBL26620538 | 0.70 | CYP2C19 (0.38) | TYMSCRBNLMNAALOX15KDM4E | |
| SCHEMBL7976084 | 0.69 | LMNA (0.44) | DHFRSLC19A1TYMSLMNAALOX15 | |
| SCHEMBL26620760 | 0.69 | CYP2C19 (0.41) | TYMSCRBNLMNATHRBMEN1 | |
| SCHEMBL25691090 | 0.68 | ALOX15 (0.39) | DHFRSLC19A1LMNAALOX15KDM4E | |
| SCHEMBL9918990 | 0.68 | CRBN (0.44) | CRBNKDM4EMEN1KMT2AMAPT | |
| SCHEMBL23980534 | 0.67 | TYMS (0.43) | DHFRSLC19A1TYMSLMNAALOX15 | |
| SCHEMBL23561101 | 0.67 | CRBN (0.38) | DHFRSLC19A1TYMSCRBNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155690-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | ARVINAS OPERATIONS, INC. | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155690-A1 | CEREBLON LIGANDS AND BIFUNCTIONAL COMPOUNDS COMPRISING THE SAME | CRBN, CBL, MDM2 | DHFR 2675/4885SLC19A1 4107/4885TYMS 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.