Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377706 | 0.95 | AVPR1A (0.33) | DUTALDH1A1POLBADRB2MAPT | |
| SCHEMBL22449985 | 0.82 | ALDH1A1 (0.32) | ALDH1A1POLBTSHRGAAGRM5 | |
| SCHEMBL15307694 | 0.81 | ALDH1A1 (0.38) | ALDH1A1POLBMAPTTSHRAVPR1A | |
| SCHEMBL14554712 | 0.79 | ALDH1A1 (0.31) | ALDH1A1AVPR1AGAABUB1GRM5 | |
| SCHEMBL14377656 | 0.78 | ALDH1A1 (0.39) | ALDH1A1POLBMAPTAVPR1AGAA | |
| SCHEMBL18093608 | 0.78 | ALDH1A1 (0.39) | ALDH1A1POLBMAPTAVPR1AGAA | |
| SCHEMBL14377695 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1POLBMAPTTSHRGAA | |
| SCHEMBL21133771 | 0.76 | ALDH1A1 (0.37) | ALDH1A1POLBTSHRMEN1KMT2A | |
| SCHEMBL14377658 | 0.76 | RIPK1 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14376956 | 0.76 | ALDH1A1 (0.36) | ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157049-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157049-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | DUT 2058/4885ALDH1A1 2648/4885POLB 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.