Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 3/20 | 0.66 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | C1S | P09871 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397441 | 1.00 | TPH1 (0.66) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL288201 | 1.00 | TPH1 (0.66) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL1064252 | 1.00 | TPH1 (0.66) | TPH1SLC7A5PTGS1ALPIPKM | |
| Hydrochloric Acid SCHEMBL5279289 | 0.98 | TPH1 (0.64) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL20714851 | 0.86 | PRSS1 (0.50) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL668746 | 0.85 | TPH1 (0.70) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL21690013 | 0.85 | TPH1 (0.70) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL668747 | 0.85 | TPH1 (0.70) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL7272904 | 0.85 | TPH1 (0.50) | TPH1SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2310526 | 0.84 | SLC7A5 (0.83) | TPH1SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025094171-A1 | SUPERHYDROPHOBIC COATING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2025-05-08 | — | — | WO | claimed |
| EP-4401555-A1 | ANTIMICROBIAL PEPTIDES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2024-07-24 | — | — | EP | claimed |
| WO-2023042201-A1 | ANTIMICROBIAL PEPTIDES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2023-03-23 | — | — | WO | claimed |
| EP-2951195-B1 | ANTIFOULING MATERIALS | YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) | 2020-02-19 | — | — | EP | claimed |
| EP-3374520-A1 | BIOSENSORS | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2018-09-19 | — | — | EP | claimed |
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2018-07-10 | — | — | US | claimed |
| EP-2836485-B1 | CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS | POLYPHOR AG (CH) | 2018-01-10 | — | — | EP | claimed |
| US-9695191-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | POLYPHOR AG (CH) | 2017-07-04 | — | — | US | claimed |
| WO-2017081684-A1 | BIOSENSORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2017-05-18 | — | — | WO | claimed |
| US-9631100-B2 | Antifouling materials | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2017-04-25 | — | — | US | claimed |
| US-6056940-A | TECHNETIUM-99M COMPLEXING MOIETY COVALENTLY LINKED TO A PLATELET GLYCOPROTEIN IIB/IIIA RECEPTOR BINDING MOIETY HAVING A MOLECULAR WEIGHT OF LESS THAN 10,000 DALTONS | DIATIDE, INC. (US) | 2000-05-02 | — | — | US | claimed |
| WO-2000015658-A1 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-03-23 | — | — | WO | claimed |
| EP-0987274-A1 | Factor VIIa Inhibitors | Hoechst Marion Roussel Deutschland GmbH (DE) | 2000-03-22 | — | — | EP | claimed |
| WO-1999046272-A1 | SERINE PEPTIDASE MODULATORS | FONDATECH BENELUX N.V. (BE) | 1999-09-16 | — | — | WO | claimed |
| US-5830856-A | RADIOLABELED SCINTIGRAPHIC IMAGING | DIATIDE, INC. (US) | 1998-11-03 | — | — | US | claimed |
| EP-0772460-A1 | RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING | DIATECH, INC. (US) | 1997-05-14 | — | — | EP | claimed |
| EP-0693941-A1 | RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING | Diatide, Inc. (US) | 1996-01-31 | — | — | EP | claimed |
| WO-1995033496-A1 | RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING | DIATECH, INC. (US) | 1995-12-14 | — | — | WO | claimed |
| WO-1994023758-A1 | RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING | DIATECH, INC. (US) | 1994-10-27 | — | — | WO | claimed |
| WO-1993000108-A1 | NOVEL INHIBITORS OF PLATELET AGGREGATION | CORVAS INTERNATIONAL, INC. (US) | 1993-01-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10017481-B2 | Conformationally constrained, fully synthetic macrocyclic compounds | CTSE, CTSB, CTSS | TPH1 244/4885SLC7A5 1084/4885PTGS1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.