Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033278 | 1.00 | KMT2A (0.44) | KMT2AMEN1PYCR1ACHESMPD1 | |
| SCHEMBL21963819 | 0.83 | KMT2A (0.48) | KMT2AMEN1PYCR1ACHESMPD1 | |
| SCHEMBL22010534 | 0.81 | KMT2A (0.57) | KMT2AMEN1PYCR1ACHESMPD1 | |
| SCHEMBL21963860 | 0.79 | KMT2A (0.44) | KMT2AMEN1PYCR1ACHESMPD1 | |
| SCHEMBL22010531 | 0.78 | MTNR1B (0.40) | KMT2AMEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31033275 | 0.76 | KDM4E (0.38) | KMT2AMEN1ACHEHSD17B2 | |
| SCHEMBL9416597 | 0.70 | ACHE (0.59) | KMT2AMEN1PYCR1ACHETAS2R14 | |
| SCHEMBL21964003 | 0.68 | MEN1 (0.39) | KMT2AMEN1 | |
| SCHEMBL30093216 | 0.67 | CALM1 (0.60) | KMT2AMEN1ACHEBCHE | |
| SCHEMBL4611890 | 0.67 | PYCR1 (0.69) | KMT2AMEN1PYCR1ACHESMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |