Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963819 | 0.86 | KMT2A (0.48) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL22010529 | 0.81 | KMT2A (0.44) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL31033278 | 0.81 | KMT2A (0.44) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL21964039 | 0.76 | KMT2A (0.57) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL4611890 | 0.71 | PYCR1 (0.69) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL16039094 | 0.68 | ACHE (0.76) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL22010475 | 0.67 | KMT2A (0.48) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL9821873 | 0.66 | CYP2D6 (0.68) | KMT2AMEN1ACHESMPD1TDP1 | |
| SCHEMBL20804510 | 0.66 | PYCR1 (0.62) | KMT2AMEN1ACHESMPD1PYCR1 | |
| SCHEMBL9416597 | 0.66 | ACHE (0.59) | KMT2AMEN1ACHEPYCR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272302-A | Antibiotic compounds, process for their manufacture, pharmaceutical compositions containing them and their use | 德彪药业国际股份公司 | 2021-08-17 | — | — | CN | disclosed |
| WO-2020099341-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2020-05-22 | — | — | WO | disclosed |