SCHEMBL2201118

SCHEMBL2201118

COc1cccc2c(B3OC(C)(C)C(C)(C)O3)c3cccc(OC)c3cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NQO1 P15559 1/20 0.38
▸ EGFR P00533 1/20 0.37
▸ CSF1R P07333 1/20 0.36
▸ IDO1 P14902 1/20 0.36
▸ NQO2 P16083 1/20 0.36
▸ PRKDC P78527 1/20 0.35
▸ EP300 Q09472 1/20 0.35
▸ KAT8 Q9H7Z6 1/20 0.35
▸ CYP2A6 P11509 1/20 0.35
▸ TNKS O95271 2/20 0.35
▸ TNKS2 Q9H2K2 1/20 0.35
▸ LPL P06858 3/20 0.34
▸ LIPG Q9Y5X9 3/20 0.34
▸ HPGD P15428 3/20 0.34
▸ MEN1 O00255 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CDK2 P24941 1/20 0.33
▸ HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13855188 0.84 MAOA (0.40) EGFRCSF1RNQO2LPLLIPG
SCHEMBL28915005 0.83 CA1 (0.41) EGFRCSF1RLPLLIPGHPGD
SCHEMBL5784094 0.79 IDO1 (0.41) EGFRCSF1RIDO1NQO2EP300
SCHEMBL2018549 0.78 LPL (0.50) LPLLIPGCA12CA1CA2
SCHEMBL2192910 0.77 NQO1 (0.46) NQO1EGFRCSF1RLPLLIPG
SCHEMBL26647695 0.77 CSF1R (0.38) NQO1EGFRCSF1RNQO2LPL
SCHEMBL24558186 0.75 ALDH1A1 (0.46) EGFRIDO1EP300KAT8LPL
SCHEMBL30526881 0.75 EGFR (0.37) EGFRCSF1RNQO2LPLLIPG
SCHEMBL26058397 0.75 LPL (0.41) EGFRLPLLIPGHPGDALDH1A1
SCHEMBL17071924 0.75 KMT2A (0.40) EGFRCSF1RIDO1EP300KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470543-B1 VISIBLE/NIR PHOTODETECTORS UNIV MICHIGAN REGENTS (US) 2017-07-26 — — EP disclosed
US-20150318479-A1 Visible/Near-Infrared Porphyrin-Tape/C60 Organic Photodetectors UNIVERSITY OF SOUTHERN CALIFORNIA 2015-11-05 — — US disclosed
US-9017826-B2 Visible/near-infrared porphyrin-tape/C60 organic photodetectors THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2015-04-28 — — US disclosed
EP-2470543-A1 VISIBLE/NIR PHOTODETECTORS The Regents of the University of Michigan (US) 2012-07-04 — — EP disclosed
US-20110168984-A1 VISIBLE/NEAR-INFRARED PORPHYRIN-TAPE/C60 ORGANICPHOTODETECTORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2011-07-14 — — US disclosed
WO-2011028610-A1 VISIBLE/NIR PHOTODETECTORS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2011-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318479-A1 Visible/Near-Infrared Porphyrin-Tape/C60 Organic Photodetectors PAH, PPOX, AHR NQO1 2479/4885EGFR 3357/4885CSF1R 4381/4885
US-20110168984-A1 VISIBLE/NEAR-INFRARED PORPHYRIN-TAPE/C60 ORGANICPHOTODETECTORS PAH, PPOX, AHR NQO1 2294/4885EGFR 3430/4885CSF1R 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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