Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22011530 | 0.92 | ALOX5 (0.32) | CRHBPCRHR2KEAP1NFE2L2ALOX5 | |
| SCHEMBL19986092 | 0.89 | CRHBP (0.36) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL17341544 | 0.89 | CRHBP (0.37) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL17405533 | 0.89 | KEAP1 (0.37) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL17405650 | 0.88 | CRHBP (0.36) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL17405734 | 0.85 | ALOX5 (0.35) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL17341547 | 0.84 | CRHBP (0.36) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL17341548 | 0.84 | ALOX5 (0.36) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL17341620 | 0.84 | ALOX5 (0.36) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL16275615 | 0.84 | ALOX5 (0.35) | CRHBPCRHR2KEAP1NFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12035625-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| US-12035625-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2024-07-09 | — | — | US | disclosed |
| EP-3880682-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-14 | — | — | EP | disclosed |
| US-20220006030-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-01-06 | — | — | US | disclosed |
| WO-2020099307-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220006030-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | ZYX, RER1, AOC2 | CRHBP 4475/4885CRHR2 1820/4885KEAP1 928/4885 |
| US-12035625-B2 | Materials for organic electroluminescent devices | ZYX, RER1, AOC2 | CRHBP 4475/4885CRHR2 1820/4885KEAP1 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.