Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CFB | P00751 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11966002 | 0.83 | KIF11 (0.45) | TTRALBCSNK1DCSNK1A1GSK3B | |
| SCHEMBL24355315 | 0.82 | AR (0.33) | TTRALBALDH1A1CYP11B2CYP2A6 | |
| SCHEMBL30602887 | 0.78 | L3MBTL1 (0.37) | TTRALBCSNK1DCSNK1A1GSK3B | |
| SCHEMBL24480874 | 0.78 | L3MBTL1 (0.37) | TTRALBCSNK1DCSNK1A1GSK3B | |
| SCHEMBL10013306 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CNR2CA2POLBTYR | |
| SCHEMBL18288154 | 0.78 | PGK1 (0.43) | ALDH1A1CYP11B2CNR2CA2POLB | |
| SCHEMBL11954934 | 0.78 | KIF11 (0.44) | TTRALBALDH1A1CYP2A6KIF11 | |
| SCHEMBL30646948 | 0.78 | KIF11 (0.44) | TTRALBALDH1A1CYP2A6KIF11 | |
| SCHEMBL19475025 | 0.75 | CA2 (0.41) | ALDH1A1L3MBTL1CA2 | |
| SCHEMBL24592637 | 0.75 | CSNK1A1 (0.33) | TTRALBCSNK1DCSNK1A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |