SCHEMBL2201229

SCHEMBL2201229

C[Si](C)(c1cccc(N)c1O)c1cccc(N)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.42
CYP3A4 P08684 5/20 0.39
TSHR P16473 4/20 0.39
PIK3CA P42336 1/20 0.39
ALOX15 P16050 3/20 0.37
ALDH1A1 P00352 6/20 0.35
TDP1 Q9NUW8 3/20 0.35
HSD17B10 Q99714 3/20 0.35
HPGD P15428 3/20 0.35
CD44 P16070 1/20 0.34
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PKM P14618 1/20 0.32
LMNA P02545 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
GAA P10253 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2201228 0.77 G6PD (0.42) MMP2CYP3A4TSHRPIK3CAALOX15
SCHEMBL6468335 0.75 CYP3A4 (0.47) CYP3A4TSHRPIK3CAALOX15ALDH1A1
SCHEMBL1172644 0.74
SCHEMBL33788 0.73
SCHEMBL4867594 0.73 ALDH1A1 (0.65) MMP2CYP3A4TSHRPIK3CAALOX15
SCHEMBL29357959 0.73
Hydrochloric Acid SCHEMBL10875382 0.72 MMP2 (0.54) MMP2CYP3A4TSHRPIK3CAALOX15
Bromide SCHEMBL4899892 0.71 ALDH1A1 (0.62) MMP2CYP3A4TSHRPIK3CAALOX15
Hydrochloric Acid SCHEMBL6570703 0.71 ALDH1A1 (0.62) MMP2CYP3A4TSHRPIK3CAALOX15
SCHEMBL5556 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 MMP2 2961/4885CYP3A4 4337/4885TSHR 4306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.