SCHEMBL2201228

SCHEMBL2201228

C[Si](C)(c1cccc(O)c1N)c1cccc(O)c1N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
ALOX15 P16050 4/20 0.37
TSHR P16473 1/20 0.37
PLAU P00749 2/20 0.36
NCF1 P14598 1/20 0.36
CYP1A2 P05177 1/20 0.36
TDP1 Q9NUW8 3/20 0.36
ALDH1A1 P00352 3/20 0.36
LMNA P02545 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 3/20 0.36
EGFR P00533 2/20 0.36
CA2 P00918 2/20 0.36
FYN P06241 2/20 0.36
MMP9 P14780 2/20 0.36
RECQL P46063 2/20 0.36
ADAMTS4 O75173 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2201229 0.77 MMP2 (0.42) CASP7ALOX15TSHRCYP1A2TDP1
SCHEMBL10340777 0.75 ALDH1A1 (0.47) ALOX15TSHRCYP1A2TDP1ALDH1A1
SCHEMBL69654 0.74
Hydrochloric Acid SCHEMBL766671 0.72 G6PD (0.54) G6PDCASP7CASP6ALOX15TSHR
SCHEMBL29486565 0.69
SCHEMBL103071 0.69
SCHEMBL2489063 0.69
SCHEMBL21546187 0.67 IDO1 (0.40) TSHRTDP1ALDH1A1HPGDHSD17B10
SCHEMBL29623283 0.67
SCHEMBL564030 0.67 CASP7 (0.50) G6PDCASP7CASP6ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1909142-B1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES (JP) 2015-06-24 EP disclosed
US-7977028-B2 Photosensitive resin composition and adhesion promoter TORAY INDUSTRIES, INC. (JP) 2011-07-12 US disclosed
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER TORAY INDUSTRIES, INC. (JP) 2009-05-14 US disclosed
EP-1909142-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION ENHANCER TORAY INDUSTRIES, INC. (JP) 2008-04-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090123867-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ADHESION PROMOTER PCNA, TERB1, SMC2 G6PD 4017/4885CASP7 4530/4885CASP6 4346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.