Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22012427 | 0.85 | FFAR2 (0.35) | LOXL2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL28550887 | 0.79 | GCK (0.33) | LOXL2 | |
| SCHEMBL27174967 | 0.79 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL22020356 | 0.79 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL31206589 | 0.75 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL22013627 | 0.73 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL22811829 | 0.73 | TRPM5 (0.31) | — | |
| SCHEMBL18760825 | 0.72 | SLC6A3 (0.30) | — | |
| SCHEMBL25933310 | 0.71 | NOS1 (0.40) | — | |
| SCHEMBL14309114 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |