Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.31 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962257 | 0.84 | NSD2 (0.33) | NSD2PARGLMNAMAPTSMN1; SMN2 | |
| SCHEMBL21962402 | 0.73 | HSD17B2 (0.36) | NSD2PARGLMNAMAPTSMN1; SMN2 | |
| SCHEMBL21962838 | 0.72 | LMNA (0.32) | PARGLMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL23093222 | 0.69 | NSD2 (0.44) | NSD2PARGLMNAMAPTSMN1; SMN2 | |
| SCHEMBL7512043 | 0.69 | L3MBTL1 (0.44) | NSD2LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL21962711 | 0.68 | USP30 (0.35) | LMNAMEN1KMT2A | |
| SCHEMBL22012708 | 0.68 | MMP13 (0.38) | LMNAMAPTKDM4E | |
| SCHEMBL11054324 | 0.67 | KMT2A (0.43) | NSD2PARGLMNAMAPTSMN1; SMN2 | |
| SCHEMBL21962347 | 0.66 | LMNA (0.41) | LMNAMAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL1523222 | 0.66 | ALDH1A1 (0.54) | LMNAMAPTSMN1; SMN2MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102576-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |