Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701209 | 0.88 | HTT (0.67) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL29245495 | 0.87 | PKM (0.60) | KMT2ALMNAALOX5PKMALDH1A1 | |
| SCHEMBL22015349 | 0.86 | TDP1 (0.62) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL27957224 | 0.86 | MMP1 (0.56) | KMT2AALOX5PKMALDH1A1KDM4E | |
| SCHEMBL8886989 | 0.85 | HSD17B2 (0.67) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL17769825 | 0.85 | MAPT (0.61) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL24983859 | 0.83 | HPGD (0.57) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL30141079 | 0.83 | HPGD (0.57) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL7720496 | 0.82 | LMNA (0.60) | KMT2ASLC6A2SLC6A3TDP1LMNA | |
| SCHEMBL6282770 | 0.82 | KMT2A (0.81) | KMT2ASLC6A2SLC6A3TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220009892-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | INCILIA THERAPEUTICS PRIVATE LIMITED (IN) | 2022-01-13 | — | — | US | disclosed |
| WO-2020100169-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | INCILIA THERAPEUTICS PRIVATE LIMITED (IN) | 2020-05-22 | — | — | WO | disclosed |
| CN-103751162-A | Application of benzyl-4-hydroxy-3,5-dimethoxy benzoate in preparation of drugs for treating acute inflammation | NANTONG REPAIR AIR CHEM BIOENG | 2014-04-30 | — | — | CN | disclosed |
| CN-103751162-A | Application of benzyl-4-hydroxy-3,5-dimethoxy benzoate in preparation of drugs for treating acute inflammation | NANTONG REPAIR AIR CHEM BIOENG | 2014-04-30 | — | — | CN | disclosed |
| CN-103751162-A | Application of benzyl-4-hydroxy-3,5-dimethoxy benzoate in preparation of drugs for treating acute inflammation | NANTONG REPAIR AIR CHEM BIOENG | 2014-04-30 | — | — | CN | disclosed |
| CN-103751167-A | Application of benzyl-4-hydroxy-3,5-dimethoxy benzoate in preparation of drugs for treating or preventing rheumatoid arthritis | NANTONG REPAIR AIR CHEM BIOENG | 2014-04-30 | — | — | CN | disclosed |
| CN-103751167-A | Application of benzyl-4-hydroxy-3,5-dimethoxy benzoate in preparation of drugs for treating or preventing rheumatoid arthritis | NANTONG REPAIR AIR CHEM BIOENG | 2014-04-30 | — | — | CN | disclosed |
| CN-103751167-A | Application of benzyl-4-hydroxy-3,5-dimethoxy benzoate in preparation of drugs for treating or preventing rheumatoid arthritis | NANTONG REPAIR AIR CHEM BIOENG | 2014-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009892-A1 | SUBSTITUTED PYRIDINE CARBOXYLIC ACIDS, THEIR PREPARATION METHOD AND COMPOSITIONS THEREOF | PC, PCCA, GLS2 | KMT2A 2224/4885SLC6A2 1851/4885SLC6A3 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.