Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.36 |
| ▸ | HTR3B | O95264 | 3/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17642641 | 0.78 | MEN1 (0.50) | ADRB1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL22015789 | 0.76 | ALDH1A1 (0.50) | ADRB1KDM4EKMT2AALDH1A1GAA | |
| SCHEMBL22537561 | 0.76 | AKR1C3 (0.42) | ADRB1HTR3ASIRT6KDM4EKMT2A | |
| SCHEMBL22014810 | 0.75 | ALDH1A1 (0.49) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL17320506 | 0.73 | KDM4E (0.46) | KDM4EKMT2AALDH1A1GAAMAPT | |
| SCHEMBL22015092 | 0.73 | HIF1A (0.50) | KDM4EKMT2AALDH1A1GAAMAPT | |
| SCHEMBL22014811 | 0.72 | KDM4E (0.50) | ADRB1HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL25387770 | 0.72 | ALDH1A1 (0.42) | KDM4EKMT2AALDH1A1GAAMAPT | |
| SCHEMBL19491900 | 0.68 | SIRT6 (0.44) | SIRT6KDM4EKMT2AALDH1A1GAA | |
| SCHEMBL4519141 | 0.66 | ADRB1 (0.58) | ADRB1HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099886-A1 | LOX INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-05-22 | — | — | WO | disclosed |