SCHEMBL22015095

SCHEMBL22015095

FC(F)(F)c1ccc(OI)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
KIF11 P52732 6/20 0.44
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
MAOB P27338 3/20 0.42
IDO1 P14902 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
PLAU P00749 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
TRPV6 Q9H1D0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12230428 0.84 PDE2A (0.42) CA1CA2CA9ALDH1A1TSHR
SCHEMBL11148692 0.78 CA1 (0.52) CA1CA2CA9KIF11ALDH1A1
SCHEMBL1685383 0.78 CA1 (0.52) CA1CA2CA9KIF11ALDH1A1
SCHEMBL63468 0.76 ALDH1A1 (0.67) KIF11ALDH1A1TSHRIDO1HTR3E
SCHEMBL29377645 0.76 LTA4H (0.50) CA1CA2CA9KIF11ALDH1A1
SCHEMBL92001 0.76 CA1 (0.50) CA1CA2CA9KIF11ALDH1A1
SCHEMBL24024094 0.74 IDO1 (0.41) IDO1CES2
SCHEMBL1515698 0.74 MAPT (0.52) CA1CA2CA9KIF11ALDH1A1
SCHEMBL20980178 0.74 HPGD (0.46) CA1CA2CA9ALDH1A1TSHR
SCHEMBL16578067 0.74 KIF11 (0.48) CA1CA2CA9KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020100783-A1 COLORING COMPOSITION 住友化学株式会社 2020-05-22 WO disclosed