Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015903 | 0.95 | KMT2A (0.57) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL22019519 | 0.93 | KMT2A (0.47) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL176438 | 0.83 | MEN1 (0.47) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL1593720 | 0.78 | KMT2A (0.45) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL9067824 | 0.78 | SMN1; SMN2 (0.49) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL9657085 | 0.76 | ALDH5A1 (0.48) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL30578615 | 0.76 | TSHR (0.46) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL31516973 | 0.76 | ALDH1A1 (0.48) | KMT2AMEN1MAPTHPGDALDH1A1 | |
| SCHEMBL3810149 | 0.75 | MEN1 (0.42) | KMT2AMEN1HPGDALDH1A1TSHR | |
| SCHEMBL31516874 | 0.75 | ALDH1A1 (0.51) | KMT2AMEN1MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC. (US) | 2022-01-06 | — | — | US | disclosed |
| WO-2020099518-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY DETREY GMBH (DE) | 2020-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DUOX2, DUOX1, QSOX1 | KMT2A 1673/4885MEN1 2939/4885MAPT 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.