SCHEMBL2201670

SCHEMBL2201670

CN(C)C(=O)c1cccnc1Cl

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 2/20 0.46
EGFR P00533 2/20 0.46
NPC1 O15118 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
PIK3C3 Q8NEB9 1/20 0.44
HTT P42858 1/20 0.43
GFER P55789 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL257468 0.83 LMNA (0.54) SMN1; SMN2LMNAPOLBEGFRNPC1
SCHEMBL9364204 0.83 SMN1; SMN2 (0.54) SMN1; SMN2LMNAPOLBL3MBTL1KMT2A
SCHEMBL8301115 0.83 LMNA (0.54) SMN1; SMN2LMNAPOLBEGFRNPC1
SCHEMBL29865799 0.83 LMNA (0.54) SMN1; SMN2LMNAPOLBEGFRNPC1
SCHEMBL8067070 0.82 LMNA (0.58) SMN1; SMN2LMNAPOLBEGFRNPC1
SCHEMBL12300200 0.82 POLB (0.64) SMN1; SMN2LMNAPOLBEGFRNPC1
SCHEMBL9737760 0.81 LMNA (0.56) SMN1; SMN2LMNAPOLBEGFRNPC1
SCHEMBL1044152 0.81 SMN1; SMN2 (0.56) SMN1; SMN2LMNAPOLBL3MBTL1KMT2A
SCHEMBL1034880 0.79 NAPRT (0.63) SMN1; SMN2LMNAL3MBTL1KMT2AMEN1
SCHEMBL12562088 0.79 P2RX7 (0.56) SMN1; SMN2LMNAL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192273-A Preparation method of 2-chloro-N, N-dimethyl nicotinamide 山东京博农化科技股份有限公司 2025-06-24 CN claimed
CN-120058601-A Preparation process of nicosulfuron intermediate 2-chloro-N, N-dimethyl nicotinamide 河北临港化工有限公司 2025-05-30 CN claimed
CN-115850166-B Continuous preparation method of 2-sulfamoyl-N, N-dimethyl nicotinamide 山东京博生物科技有限公司 2025-04-25 CN claimed
CN-119390643-A Method for continuously preparing 2-chloro-N, N-dimethyl nicotinamide in two steps 湖北泰盛化工有限公司 2025-02-07 CN claimed
CN-118724803-A Method for preparing N, N-dimethyl-2-chloronicotinic acid amide by utilizing composite solid acid catalysis 山东京博生物科技有限公司 2024-10-01 CN claimed
CN-116903528-A Synthesis method of 2-sulfamoyl-N, N-dimethyl nicotinamide 浙江禾本科技股份有限公司 2023-10-20 CN claimed
CN-116813539-A Preparation method of 2-sulfamoyl-N, N-dimethyl nicotinamide 山东京博农化科技股份有限公司 2023-09-29 CN claimed
CN-115850166-A Continuous preparation method of 2-aminosulfonyl-N, N-dimethylnicotinamide 山东京博生物科技有限公司 2023-03-28 CN claimed
CN-113214147-B Preparation method of 2-thioether-N, N-dimethylnicotinamide 江苏先导药业有限公司 2023-03-21 CN claimed
CN-115504931-A Method for preparing sulfonylurea herbicide intermediate 江苏省激素研究所股份有限公司 2022-12-23 CN claimed
CN-112479995-B Preparation method of 2-chloro-N, N-dimethylnicotinamide 淄博新农基作物科学有限公司 2022-08-30 CN claimed
CN-114940662-A Preparation method of nicosulfuron 湖北广富林生物制剂有限公司 2022-08-26 CN claimed
CN-111925323-B Synthetic method of 2-aminosulfonyl-N, N-dimethylnicotinamide 山东京博生物科技有限公司 2022-05-31 CN claimed
CN-114163383-A Green production process of nicosulfuron intermediate nicotinamide and sulfamide 江苏丰山集团股份有限公司 2022-03-11 CN claimed
CN-114075137-A Preparation method of 2-aminosulfonyl-N, N-dimethylnicotinamide 江苏瑞邦农化股份有限公司 2022-02-22 CN claimed
CN-102329265-A Synthesis method of N, N-dimethyl-2-chloro nicotinamide JIANGSU CHANGQING AGROCHEMICAL CO LTD 2012-01-25 CN claimed
JP-1102064-A None JP disclosed
CN-121226241-A Continuous preparation method of 2-chloro-N, N-dimethyl nicotinamide 山东京博生物科技有限公司 2025-12-30 CN disclosed
US-4786734-A FOR GRASSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-22 US disclosed
EP-0237292-A2 Herbicidal pyridine sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-16 EP disclosed