Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626001 | 0.81 | RIPK1 (0.43) | LMNASMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL4406065 | 0.81 | NAPRT (0.58) | LMNASMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL2201670 | 0.81 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2EGFRPOLBHTT | |
| SCHEMBL5787503 | 0.81 | RIPK1 (0.40) | LMNASMN1; SMN2EGFRALDH1A1NPC1 | |
| SCHEMBL10640376 | 0.80 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2EGFRPOLBHTT | |
| SCHEMBL8301115 | 0.79 | LMNA (0.54) | LMNASMN1; SMN2EGFRPOLBHTT | |
| SCHEMBL8067070 | 0.78 | LMNA (0.58) | LMNASMN1; SMN2EGFRPOLBHTT | |
| SCHEMBL9735902 | 0.78 | MAPT (0.44) | LMNASMN1; SMN2POLBHTTALDH1A1 | |
| SCHEMBL13415863 | 0.77 | LMNA (0.61) | LMNASMN1; SMN2EGFRPOLBHTT | |
| SCHEMBL10517816 | 0.77 | RIPK1 (0.42) | LMNASMN1; SMN2POLBHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079363-A | From an alkoxypyridine and an indole derivative, antitumor and antileukemia agents | SANOFI (FR) | 1992-01-07 | — | — | US | disclosed |