Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061927 | 0.77 | ALDH1A1 (0.41) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL5609776 | 0.75 | ELANE (0.41) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL2203411 | 0.75 | POLB (0.46) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL5609770 | 0.75 | ALDH1A1 (0.39) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL2197815 | 0.75 | SIGMAR1 (0.36) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL1057367 | 0.74 | IFNAR1 (0.47) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL2202057 | 0.72 | CYP2A6 (0.54) | TSHRHSD17B10CYP2A6ALDH1A1TDP1 | |
| SCHEMBL2200144 | 0.71 | ALOX5 (0.47) | TSHRHSD17B10ALDH1A1TDP1KDM4E | |
| SCHEMBL18297552 | 0.70 | PDE7A (0.32) | ALDH1A1KDM4EMAPT | |
| SCHEMBL3283218 | 0.70 | GAA (0.39) | ALDH1A1TDP1CYP1A2KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964861-B1 | ACETYLENE-BASED POLYMER | NAT INST OF ADVANCED IND SCIEN (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7977441-B2 | Acetylene-based polymer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20090253872-A1 | Acetylene-Based Polymer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-1964861-A1 | ACETYLENE POLYMER | National Institute of Advanced Industrial Science and Technology (JP) | 2008-09-03 | — | — | EP | disclosed |