SCHEMBL2201728

SCHEMBL2201728

CCCCC/C=C/C/C=C/CCCCCCCC(=O)O[C@H]1[C@H](O)[C@@H](CO)OC(O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TLR4 O00206 4/20 0.56
▸ TK2 O00142 4/20 0.49
▸ MGLL Q99685 1/20 0.49
▸ CNR1 P21554 1/20 0.46
▸ CNR2 P34972 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12427212 1.00 TLR4 (0.56) TLR4TK2MGLLCNR1CNR2
SCHEMBL2201730 1.00 TLR4 (0.56) TLR4TK2MGLLCNR1CNR2
SCHEMBL13818326 1.00 TLR4 (0.56) TLR4TK2MGLLCNR1CNR2
SCHEMBL2201735 1.00 TLR4 (0.56) TLR4TK2MGLLCNR1CNR2
SCHEMBL2200160 0.96 TLR4 (0.54) TLR4TK2CNR2
SCHEMBL2200165 0.96 TLR4 (0.54) TLR4TK2CNR2
SCHEMBL2200169 0.96 TLR4 (0.54) TLR4TK2CNR2
SCHEMBL2309050 0.92 TLR4 (0.55) TLR4TK2MGLLCNR1CNR2
SCHEMBL2309057 0.92 TLR4 (0.55) TLR4TK2MGLLCNR1CNR2
SCHEMBL2309054 0.92 TLR4 (0.55) TLR4TK2MGLLCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 — — EP claimed
EP-2861205-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2015-04-22 — — EP claimed
WO-2013186485-A1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER, METHOD THEREFOR, AND USE THEREOF L'OREAL (FR) 2013-12-19 — — WO claimed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 — — EP claimed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 — — US claimed
US-20100143279-A1 COSMETIC/DERMATOLOGICAL COMPOSITIONS COMPRISING A DERIVATIVE OF GLUCOSE AND OF VITAMIN F AND A SPECIFIC SURFACTANT L'OREAL (FR) 2010-06-10 — — US claimed
EP-1837341-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'Oréal (FR) 2007-09-26 — — EP claimed
EP-1371658-B1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation OREAL (FR) 2007-09-12 — — EP claimed
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. 2007-05-31 — — US claimed
US-20060177403-A1 Cosmetic/dermatological compositions comprising a derivative of glucose and of vitamin F and A specific surfactant L'OREAL (FR) 2006-08-10 — — US claimed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 — — US claimed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 — — EP claimed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 — — WO claimed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 — — US claimed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 — — EP claimed
EP-1688128-B1 Method for treating keratinic fibres and the scalp with a composition containing a derivative of glucose and vitamin F L'ORÉAL (FR) 2018-03-07 — — EP disclosed
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 — — EP disclosed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 — — WO disclosed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 — — US disclosed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060177403-A1 Cosmetic/dermatological compositions comprising a derivative of glucose and of vitamin F and A specific surfactant HKDC1, ADH1B, HK1 TLR4 3459/4885TK2 720/4885MGLL 859/4885
US-20100143279-A1 COSMETIC/DERMATOLOGICAL COMPOSITIONS COMPRISING A DERIVATIVE OF GLUCOSE AND OF VITAMIN F AND A SPECIFIC SURFACTANT HKDC1, ADH1B, HK1 TLR4 3459/4885TK2 720/4885MGLL 859/4885
US-20070123471-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885TK2 861/4885MGLL 349/4885
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885TK2 861/4885MGLL 349/4885
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin CUTA, SCD5, SCD TLR4 685/4885TK2 3873/4885MGLL 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback