Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915842 | 1.00 | APP (0.46) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL14436656 | 0.93 | APP (0.44) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL14436330 | 0.93 | RELA (0.56) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL14436331 | 0.93 | NFE2L2 (0.43) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL14436657 | 0.93 | APP (0.44) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL23820710 | 0.90 | APP (0.40) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL18327869 | 0.89 | TRPA1 (0.51) | RELAALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL830304 | 0.89 | TRPA1 (0.51) | RELAALDH1A1KDM4ECYP1A2MAPT | |
| SCHEMBL14437326 | 0.88 | APP (0.41) | APPRELAPRKCQPRKCDALDH1A1 | |
| SCHEMBL9915635 | 0.88 | APP (0.38) | APPRELAPRKCQPRKCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20020185634-A1 | Two-photon or higher-order absorbing optical materials and methods of use | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-12-12 | — | — | US | disclosed |
| US-6267913-B1 | IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2001-07-31 | — | — | US | disclosed |
| WO-1998021521-A9 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE | CALIFORNIA INST OF TECHN (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1998021521-A1 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-05-22 | — | — | WO | disclosed |