SCHEMBL22018362

SCHEMBL22018362

CC(NC(=O)CNC(=O)CNC(=O)CNC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C1CCCN1)C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 2/20 0.38
▸ NAA50 Q9GZZ1 1/20 0.37
▸ APLNR P35414 1/20 0.37
▸ CALCRL Q16602 1/20 0.35
▸ MAPK8 P45983 1/20 0.34
▸ MAPK9 P45984 1/20 0.34
▸ MAPK10 P53779 1/20 0.34
▸ KEAP1 Q14145 1/20 0.34
▸ OXTR P30559 3/20 0.34
▸ TERT O14746 1/20 0.33
▸ NMUR2 Q9GZQ4 1/20 0.33
▸ NMUR1 Q9HB89 1/20 0.33
▸ AVPR2 P30518 2/20 0.33
▸ AVPR1A P37288 2/20 0.33
▸ AVPR1B P47901 2/20 0.33
▸ P2RY12 Q9H244 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23871517 0.99 FAP (0.38) FAPNAA50APLNRCALCRLMAPK8
SCHEMBL26391856 0.95 APLNR (0.38) FAPNAA50APLNRCALCRLMAPK8
SCHEMBL29308497 0.94 FAP (0.36) FAPNAA50APLNRCALCRLMAPK8
SCHEMBL29308274 0.93 MAPK8 (0.34) FAPNAA50APLNRCALCRLMAPK8
SCHEMBL22922802 0.92 NAA50 (0.42) NAA50APLNRCALCRLMAPK8MAPK9
SCHEMBL29308489 0.91 NAA50 (0.39) FAPNAA50APLNRCALCRLMAPK8
SCHEMBL29308708 0.91 PREP (0.37) FAPCALCRLTERT
SCHEMBL29308258 0.90 CTSD (0.34) FAPNAA50APLNRMAPK8MAPK9
SCHEMBL26388157 0.90 FAP (0.36) FAPNAA50APLNRKEAP1OXTR
SCHEMBL29308229 0.90 CTSD (0.37) NAA50APLNRCALCRLMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
WO-2021191689-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2021-09-30 — — WO disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR FAP 1121/4885NAA50 3702/4885APLNR 85/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 FAP 530/4885NAA50 4530/4885APLNR 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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