SCHEMBL26388157

SCHEMBL26388157

CC(C)N(C(=O)CNC(=O)CNC(=O)CNC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C1CCCN1)C(C)C(=O)NCC(=O)N1CCCC1C(=O)NCC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 2/20 0.36
▸ NAA50 Q9GZZ1 1/20 0.35
▸ KEAP1 Q14145 1/20 0.33
▸ OPRM1 P35372 2/20 0.33
▸ OPRD1 P41143 2/20 0.33
▸ OXTR P30559 2/20 0.32
▸ TERT O14746 1/20 0.32
▸ P2RY12 Q9H244 1/20 0.32
▸ KDM1A O60341 1/20 0.32
▸ CCKBR P32239 1/20 0.31
▸ APLNR P35414 1/20 0.31
▸ GLO1 Q04760 1/20 0.31
▸ AVPR2 P30518 1/20 0.31
▸ AVPR1A P37288 1/20 0.31
▸ AVPR1B P47901 1/20 0.31
▸ STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308698 0.94 FAP (0.36) FAPNAA50KEAP1OPRM1OPRD1
SCHEMBL22018362 0.90 FAP (0.38) FAPNAA50KEAP1OXTRTERT
SCHEMBL23871517 0.89 FAP (0.38) FAPNAA50KEAP1OXTRTERT
SCHEMBL26391856 0.86 APLNR (0.38) FAPNAA50KEAP1OXTRKDM1A
SCHEMBL22019147 0.85 FAP (0.33) FAPNAA50OPRM1OPRD1OXTR
SCHEMBL29308258 0.85 CTSD (0.34) FAPNAA50KEAP1OXTRTERT
SCHEMBL29308497 0.84 FAP (0.36) FAPNAA50KEAP1OXTRTERT
SCHEMBL29308274 0.84 MAPK8 (0.34) FAPNAA50KEAP1OXTRTERT
SCHEMBL22922802 0.82 NAA50 (0.42) NAA50KEAP1OXTRKDM1AAPLNR
SCHEMBL29308489 0.82 NAA50 (0.39) FAPNAA50KEAP1OXTRKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR FAP 1121/4885NAA50 3702/4885KEAP1 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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