SCHEMBL22018374

SCHEMBL22018374

CCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.52
▸ APLNR P35414 2/20 0.50
▸ NMBR P28336 2/20 0.48
▸ GRPR P30550 2/20 0.48
▸ CALCR P30988 4/20 0.47
▸ HCRTR1 O43613 1/20 0.47
▸ HCRTR2 O43614 1/20 0.47
▸ CRHR1 P34998 1/20 0.45
▸ CRHR2 Q13324 1/20 0.45
▸ GLP1R P43220 1/20 0.44
▸ GCGR P47871 1/20 0.44
▸ GIPR P48546 1/20 0.44
▸ NMUR2 Q9GZQ4 1/20 0.43
▸ NMUR1 Q9HB89 1/20 0.43
▸ CTSL P07711 1/20 0.43
▸ CTSS P25774 1/20 0.43
▸ CTSK P43235 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018607 0.96 F2 (0.51) F2APLNRNMBRGRPRCALCR
SCHEMBL25524938 0.92 APLNR (0.44) F2APLNRCALCRNMUR2NMUR1
SCHEMBL25524928 0.92 APLNR (0.45) F2APLNRCALCRNMUR2NMUR1
SCHEMBL25524956 0.91 NMUR2 (0.51) F2APLNRNMUR2NMUR1
SCHEMBL25524962 0.90 NMUR2 (0.46) F2APLNRCALCRNMUR2NMUR1
SCHEMBL25524955 0.90 NMUR2 (0.52) F2NMBRGRPRCALCRNMUR2
SCHEMBL22019477 0.89 NPY2R (0.44) APLNRNMBRGRPRCALCRNMUR2
SCHEMBL25524960 0.89 RAMP3 (0.46) CALCR
SCHEMBL25524949 0.88 F2 (0.45) F2CALCRHCRTR1HCRTR2GLP1R
SCHEMBL22018604 0.88 APLNR (0.45) APLNRCALCRHCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed
US-20160244756-A1 NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2016-08-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP F2 780/4885APLNR 90/4885NMBR 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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