SCHEMBL25524956

SCHEMBL25524956

CCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NMUR2 Q9GZQ4 7/20 0.51
▸ NMUR1 Q9HB89 6/20 0.51
▸ F2 P00734 4/20 0.49
▸ KEAP1 Q14145 6/20 0.48
▸ APLNR P35414 1/20 0.47
▸ MAPK8 P45983 1/20 0.46
▸ MAPK9 P45984 1/20 0.46
▸ MAPK10 P53779 1/20 0.46
▸ TFPI P10646 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25524955 0.96 NMUR2 (0.52) NMUR2NMUR1F2
SCHEMBL22018606 0.96 OPRD1 (0.48) NMUR2F2KEAP1APLNRTFPI
SCHEMBL29308367 0.94 BCL2L1 (0.48) F2KEAP1TFPI
SCHEMBL25524938 0.94 APLNR (0.44) NMUR2NMUR1F2APLNR
SCHEMBL25524928 0.94 APLNR (0.45) NMUR2NMUR1F2APLNR
SCHEMBL22018500 0.93 APLNR (0.49) NMUR2NMUR1F2APLNR
SCHEMBL25524962 0.92 NMUR2 (0.46) NMUR2NMUR1F2APLNR
SCHEMBL22018605 0.92 NPY2R (0.51) F2TFPI
SCHEMBL25524952 0.92 NMBR (0.52) —
SCHEMBL22018374 0.91 F2 (0.52) NMUR2NMUR1F2APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP NMUR2 1237/4885NMUR1 1052/4885F2 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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