Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877092 | 0.84 | LMNA (0.45) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL8697456 | 0.84 | GABRP (0.38) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL23655471 | 0.80 | NOS3 (0.44) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL23377250 | 0.78 | SLC2A1 (0.39) | NFKB1TSHRHIF1ABLMRECQL | |
| SCHEMBL6075377 | 0.78 | TAAR1 (0.50) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL6469008 | 0.77 | NOS3 (0.46) | KDM4EADRB2ADRB1ADRB3GABRP | |
| SCHEMBL27617186 | 0.77 | KDM4E (0.44) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4074768 | 0.77 | TAAR1 (0.80) | TAAR1NFKB1TSHRHIF1AHTR3A | |
| SCHEMBL9769230 | 0.76 | ADRB2 (0.51) | NFKB1TSHRHIF1AKDM4ETDP1 | |
| SCHEMBL9769240 | 0.76 | ADRB2 (0.51) | NFKB1TSHRHIF1AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342174-B1 | METHOD FOR PRODUCING 3-AMINOBIPHENYLENE | UNIV MUENCHEN TECH (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2342174-A1 | METHOD FOR PRODUCING 3-AMINOBIPHENYLENE | Technische Universität München (DE) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010037531-A1 | METHOD FOR PRODUCING 3-AMINOBIPHENYLENE | Technische Universität München (DE) | 2010-04-08 | — | — | WO | disclosed |
| EP-1633715-B1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LTD (GB) | 2007-09-05 | — | — | EP | disclosed |
| EP-1633715-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | Pfizer Limited (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108676-A1 | 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS | PFIZER LIMITED (GB) | 2004-12-16 | — | — | WO | disclosed |
| US-5767133-A | Secondary amines as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-06-16 | — | — | US | disclosed |